Enzyme Therapeutic for Ischemia and Reperfusion Injury in Organ Transplantation.

Yan, Ran; Ren, Jie; Wen, Jing; Cao, Zheng; Wu, Di; Qin, Meng; Xu, Duo; Castillo, Roxanne et al. · Adv Mater · 2022

basic_science · Level V

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Abstract

Ischemia-reperfusion injury (IRI) remains as a critical challenge for organ transplantation. Herein, an enzyme therapeutic based on superoxide dismutase and catalase for effective mitigation of IRI and pathogen-induced liver injury is reported, providing a therapeutic for organ transplantation and other diseases.

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