New strategies to improve minimap2 alignment accuracy.
Where this comes from
- Record sourced from PubMed, PMID 34623391.
- Also identified by DOI 10.1093/bioinformatics/btab705 and PMC identifier 8652018.
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Abstract
We present several recent improvements to minimap2, a versatile pairwise aligner for nucleotide sequences. Now minimap2 v2.22 can more accurately map long reads to highly repetitive regions and align through insertions or deletions up to 100 kb by default, addressing major weakness in minimap2 v2.18 or earlier. https://github.com/lh3/minimap2.
Medical subject headings
- Software
- Algorithms