Circulation of Third-Generation Cephalosporin Resistant Salmonella Typhi in Mumbai, India.

Argimón, Silvia; Nagaraj, Geetha; Shamanna, Varun; Sravani, Dharmavaram; Vasanth, Ashwini Kodlipet; Prasanna, Akshatha; Poojary, Aruna; Bari, Anurag Kumar et al. · Clin Infect Dis · 2022

case_series · Level IV

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Abstract

We report the persistent circulation of third-generation cephalosporin resistant Salmonella Typhi in Mumbai, linked to the acquisition and maintenance of a previously characterized IncX3 plasmid carrying the ESBL gene blaSHV-12 and the fluoroquinolone resistance gene qnrB7 in the genetic context of a triple mutant also associated with fluoroquinolone resistance.

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