Usefulness of CGM-Derived Metric, the Glucose Management Indicator, to Assess Glycemic Control in Non-White Individuals With Diabetes.

Abstract

To assess the relationship between the glucose management indicator (GMI) and HbA_1c in non-White individuals with diabetes. We performed a retrospective analysis of continuous glucose monitoring metrics in individuals with diabetes divided by race into non-White and White cohorts. We evaluated 316 individuals (non-White <i>n</i> = 68; White <i>n</i> = 248). Although GMI was not different (7.6 vs. 7.7; <i>P</i> = not significant) between the cohorts, HbA_1c was higher in the non-White cohort (8.7% vs. 8.1%; <i>P</i> = 0.004). HbA_1c higher than GMI by ≥0.5% was more frequently observed in the non-White cohort (90% vs. 75%; <i>P</i> = 0.02). In the non-White cohort only, duration of hypoglycemia was longer among those with HbA_1c higher than GMI by ≥0.5% compared with those with HbA_1c and GMI within 0.5%. A differential relationship between HbA_1c and GMI in non-White versus White individuals with diabetes was observed. In non-White individuals, a greater difference between HbA_1c and GMI was associated with higher risk of hypoglycemia.