FindNonCoding: rapid and simple detection of non-coding RNAs in genomes.
basic_science · Level V
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- Record sourced from PubMed, PMID 34636849.
- Also identified by DOI 10.1093/bioinformatics/btab708 and PMC identifier 10060727.
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Abstract
Non-coding RNAs are often neglected during genome annotation due to their difficulty of detection relative to protein coding genes. FindNonCoding takes a pattern mining approach to capture the essential sequence motifs and hairpin loops representing a non-coding RNA family and quickly identify matches in genomes. FindNonCoding was designed for ease of use and accurately finds non-coding RNAs with a low false discovery rate. FindNonCoding is implemented within the DECIPHER package (v2.19.3) for R (v4.1) available from Bioconductor. Pre-trained models of common non-coding RNA families are included for bacteria, archaea and eukarya. Supplementary data are available at Bioinformatics online.
Medical subject headings
- Software
- Genome