cAAVe phaenomena: Beware of appearances!
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 34653366.
- Also identified by DOI 10.1016/j.cell.2021.09.027.
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Abstract
In this issue of Cell, Wang et al. come to the unsettling conclusion that adeno-associated viruses, despite being engineered for glia-specific expression, can become widely active in endogenous neurons, misleading researchers in their quest for efficient conversion of glia into neurons for brain repair.
Medical subject headings
- Neuroglia
- Neurons