Ketone bodies: back to a place in the sun.
Where this comes from
- Record sourced from PubMed, PMID 34688385.
- Also identified by DOI 10.1016/j.kint.2021.07.022.
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Abstract
Ketone bodies have a strong negative image in medicine because of ketoacidosis, a life-threatening complication in diabetes. However, Fang et al. report that ketone bodies exert antisenescent effects in podocytes under diabetic conditions, via activation of the nuclear factor E2-related factor 2-related antioxidative stress pathway. With recent progression of research on longevity, the beneficial effects of ketone bodies are being clarified, and a positive image of ketone bodies is gradually beginning to develop in many research fields including nephrology.
Medical subject headings
- Diabetic Ketoacidosis
- Ketone Bodies