Illuminating the path to DNA repair.

Gupta, Darshana; Beisel, Chase L · Cell · 2021

editorial · Level V

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Abstract

Diverse DNA repair pathways correct ranging types of damage and play central roles in genome editing. In this issue of Cell, two publications leverage a new high-throughput screen that links pathway genes with the outcomes of repair, yielding mechanistic insights into the repair process as well as means to shape editing outcomes.

Medical subject headings