Severe Acute Respiratory Syndrome Coronavirus 2 Messenger RNA Vaccines in Allogeneic Hematopoietic Stem Cell Transplant Recipients: Immunogenicity and Reactogenicity.

Sherman, Amy C; Desjardins, Michaël; Cheng, Chi An; Bausk, Bruce; Izaguirre, Natalie; Zhou, Guohai; Krauss, Jonathan; Tolan, Nicole et al. · Clin Infect Dis · 2022

prospective_cohort · Level II

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Abstract

The severe acute respiratory syndrome coronavirus 2 messenger RNA vaccine-induced humoral response and reactogenicity profile are described in allogeneic hematopoietic stem cell transplant (HSCT) recipients. Findings showed that 75.0% (by Simoa assay) or 80.0% (by Roche assay) of the HSCT cohort had a positive antibody response on series completion, compared with 100% in the healthy cohort.

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