Powering up microbiome-microglia interactions.
Level V
Where this comes from
- Record sourced from PubMed, PMID 34731651.
- Also identified by DOI 10.1016/j.cmet.2021.10.006.
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Abstract
Despite extensive evidence implicating the microbiota in regulating the immune system, the precise mechanisms underlying microbial control of microglial maturation remain unclear. In a methodological tour de force, Erny et al. (2021) identify acetate as an essential microbiota-derived molecule driving microglial metabolic pathways and functions during healthy and diseased states.
Medical subject headings
- Gastrointestinal Microbiome
- Microbiota