Vulvar Crohn's Disease: Clinical Features and Outcomes.

Cho, Janice M; Loftus, Edward V; Bruining, David H; Chedid, Victor G; Farraye, Francis A; Faubion, William A; Johnson, Amanda M; Kane, Sunanda V et al. · Am J Gastroenterol · 2021

retrospective_cohort · Level III

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Abstract

Vulvar involvement is a rare complication of Crohn's disease (CD). The optimal treatment of vulvar CD is unknown. We conducted a 25-year retrospective cohort study of vulvar CD from 3 referral centers. Clinical features and outcomes were studied. Fifty patients were identified. The most common vulvar symptoms were pain (74%), edema (60%), ulcerations (46%), nodules (36%), and abscess (34%). Medical management leading to symptomatic improvement varied, and 5 patients ultimately required surgery. Vulvar CD manifests with a broad spectrum of symptoms. Aggressive medical management was frequently effective, although surgery was required in 10% of cases.

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