Radiation Recall Pneumonitis on FDG PET/CT Triggered by COVID-19 Vaccination.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 34739397.
- Also identified by DOI 10.1097/RLU.0000000000003980 and PMC identifier 8820752.
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Abstract
A 67-year-old man with metastatic lung adenocarcinoma was initially treated with whole-brain radiotherapy for intracranial metastases, followed by chemotherapy and pembrolizumab. After completing 2 years of systemic therapy, the primary right lung lesion was biopsy-proven to have residual adenocarcinoma, which was then treated with radiation (6000 cGy in 15 fractions). Follow-up serial FDG PET/CT showed radiation fibrosis. Eighteen months after radiotherapy, the patient received 2 doses of an mRNA COVID-19 vaccine. FDG PET/CT performed 4 days following his second vaccine dose showed FDG-avid multistation lymphadenopathy and radiation recall pneumonitis, likely vaccination-induced and mimicking recurrent disease. This resolved spontaneously without therapy.
Medical subject headings
- COVID-19
- COVID-19 Vaccines