Comparison of Duration of Postapproval vs Pivotal Trials for Therapeutic Agents Granted US Food and Drug Administration Accelerated Approval, 2009-2018.

Wallach, Joshua D; Ramachandran, Reshma; Bruckner, Till; Ross, Joseph S · JAMA Netw Open · 2021

cross_sectional · Level IV

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Abstract

This cross-sectional study compares the duration of postapproval trials with that of the pivotal trials used as the basis for the US Food and Drug Administration’s (FDA’s) approval for all indications receiving accelerated approval from 2009-2018.

Medical subject headings