Cyclic pyrimidines jump on the anti-phage bandwagon.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 34767773.
- Also identified by DOI 10.1016/j.cell.2021.10.012.
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Abstract
Cyclic pyrimidines cCMP and cUMP were known to be present in a variety of organisms and cell types, but their biological roles remained mysterious. Tal et al. show that bacteria use cCMP and cUMP as second messengers that function in anti-phage defense.
Medical subject headings
- Bacteriophages
- Cyclic CMP