A lymphocyte-glia connection sets the pace for smoldering inflammation.

Bittner, Stefan; Zipp, Frauke · Cell · 2021

basic_science · Level V

Where this comes from

Abstract

Successful therapeutic options directly targeting disability progression in patients with multiple sclerosis (MS), a chronic inflammatory disorder of the central nervous system, are lacking. Now, a study published in Nature by Absinta and colleagues profiles a lymphocyte-glia connection at the edge of chronic active lesions that continuously drives neurodegenerative pathways.

Medical subject headings