SARS-CoV-2 Spike-Specific T-Cell Responses in Patients With B-Cell Depletion Who Received Chimeric Antigen Receptor T-Cell Treatments.

Parvathaneni, Kalpana; Torres-Rodriguez, Kyabeth; Meng, Wenzhao; Hwang, Wei-Ting; Frey, Noelle; Naji, Ali; Bhoj, Vijay G · JAMA Oncol · 2022

prospective_cohort · Level II

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Abstract

This cohort study examines the ability of patients receiving chimeric antigen receptor T-cell treatments to mount T-cell immunity in response to messenger RNA vaccines for severe acute respiratory syndrome coronavirus 2 despite substantial B-cell depletion.

Medical subject headings