The brain remembers where and how inflammation struck.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 34822782.
- Also identified by DOI 10.1016/j.cell.2021.11.002.
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Abstract
Our immune system and brain interact on multiple scales, but how the brain represents and remembers immune challenges remains unclear. In this issue of Cell, Koren et al. (2021) reveal that the brain's insular cortex stores information about inflammation in the body. Strikingly, these immunological "memory engrams" can restore the initial disease state when reactivated.
Medical subject headings
- Brain
- Insular Cortex