SARS-CoV-2 Spike Protein in Intestinal Cells of a Patient with Coronavirus Disease 2019 Multisystem Inflammatory Syndrome.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 34843710.
- Also identified by DOI 10.1016/j.jpeds.2021.11.058 and PMC identifier 8626144.
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Abstract
A previously healthy 12-year-old boy had severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-related multisystem inflammatory syndrome (MIS-C) that was rapidly fatal. Autopsy revealed the presence of a large intracardiac thrombus. SARS-CoV-2 spike protein was detected in intestinal cells, supporting the hypothesis that viral presence in the gut may be related to the immunologic response of MIS-C.
Medical subject headings
- COVID-19
- Intestines
- Spike Glycoprotein, Coronavirus