The Potential Use of Novel Plant-Derived Recombinant Human Collagen in Aesthetic Medicine.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 34847096.
- Also identified by DOI 10.1097/PRS.0000000000008784.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Recombinant human type I collagen, identical in structure and functionality to human type I collagen, was successfully expressed and extracted from genetically modified tobacco plants. Contrarily to tissue extracted protein, rhCollagen is not immunogenic and not allergenic and has an intact triple helix structure showing superior biological functionality. A photocurable rhCollagen was developed by chemically modifying the protein to allow cross-linking under illumination at various wavelengths, maintaining the protein structural and biological functions. The use of the photocurable rhCollagen in aesthetic medicine, especially as a dermal filler and as a bioink for 3D-printed breast implant is discussed in this article.
Medical subject headings
- Collagen Type I
- Esthetics
- Plant Extracts
- Recombinant Proteins
- Nicotiana