A Higher Antibody Response Is Generated With a 6- to 7-Week (vs Standard) Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine Dosing Interval.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 34849655.
- Also identified by DOI 10.1093/cid/ciab938 and PMC identifier 8690265.
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Abstract
The optimal dosing interval for severe acute respiratory syndrome coronavirus 2 vaccines remains controversial. In this prospective study, we compared serology results of paramedics vaccinated with mRNA vaccines at the recommended short (17-28 days) vs long (42-49 days) interval. We found that a long dosing interval resulted in higher spike, receptor binding domain, and spike N terminal domain antibody concentrations.
Medical subject headings
- COVID-19
- SARS-CoV-2