Response to comment on "Evaluating the cardiovascular safety of sclerostin inhibition using evidence from meta-analysis of clinical trials and human genetics".

Bovijn, Jonas; Krebs, Kristi; Chen, Chia-Yen; Boxall, Ruth; Censin, Jenny C; Ferreira, Teresa; Pulit, Sara L; Glastonbury, Craig A et al. · Sci Transl Med · 2021

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Abstract

Triangulation of evidence from clinical trials and human genetics suggests a potential excess risk of cardiovascular disease events arising from therapeutic inhibition of sclerostin.

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