Microglia modulate neurodevelopment in human neuroimmune organoids.
editorial · Level V
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- Record sourced from PubMed, PMID 34861141.
- Also identified by DOI 10.1016/j.stem.2021.11.005.
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Abstract
Dissecting contributions of microglia to human brain development and disease pathogenesis requires modeling interactions between these microglia and their local environment. In this issue of Cell Stem Cell, Popova et al. (2021) propose a transcriptomic "microglia report card" and create a neuroimmune organoid to model complex interactions involving human microglia.
Medical subject headings
- Microglia
- Organoids