Stem cell-based islet replacement therapy in diabetes: A road trip that reached the clinic.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 34861145.
- Also identified by DOI 10.1016/j.stem.2021.11.008.
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Abstract
One hundred years after the discovery of insulin, Kieffer and colleagues (Ramzy et al., 2021) and Foyt and colleagues (Shapiro et al., 2021) report interim results from a multicenter clinical trial showing insulin secretion from engrafted pluripotent stem cell-derived endocrine progenitor cells in patients with type 1 diabetes.
Medical subject headings
- Diabetes Mellitus, Type 1
- Islets of Langerhans
- Islets of Langerhans Transplantation
- Pluripotent Stem Cells