SARS-CoV-2 Interference of Influenza Virus Replication in Syrian Hamsters.

Halfmann, Peter J; Nakajima, Noriko; Sato, Yuko; Takahashi, Kenta; Accola, Molly; Chiba, Shiho; Fan, Shufang; Neumann, Gabriele et al. · J Infect Dis · 2022

basic_science · Level V

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Abstract

In hamsters, SARS-CoV-2 infection at the same time as or before H3N2 influenza virus infection resulted in significantly reduced influenza virus titers in the lungs and nasal turbinates. This interference may be correlated with SARS-CoV-2-induced expression of MX1.

Medical subject headings