Insular Stimulation Produces Mental Clarity and Bliss.

Nencha, Umberto; Spinelli, Laurent; Vulliemoz, Serge; Seeck, Margitta; Picard, Fabienne · Ann Neurol · 2022

case_report · Level V

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Abstract

For the first time, an ecstatic aura has been evoked through the electrical stimulation of the dorsal anterior insula during presurgical invasive intracerebral monitoring in a patient who did not suffer from an ecstatic form of epilepsy. This case provides more evidence that the anterior insula is the major generator of such a mystical-type experience even in individuals with no underlying brain network changes related to a preexisting ecstatic epilepsy. ANN NEUROL 2022;91:289-292.

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