Estrogen wars: The activity awakens.

López, Miguel · Cell Metab · 2021

editorial · Level V

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Abstract

The mechanisms by which estrogens modulate physical activity remain unclear. A recent article published in Nature by Krause et al. (2021) demonstrates that estradiol increases the expression of melanocortin receptor 4 in a particular subset of neurons in the ventromedial nucleus of the hypothalamus, leading to increased physical activity.

Medical subject headings