Truly Man's Best Friend: Canine Cancers Drive Drug Repurposing in Osteosarcoma.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 34880110.
- Also identified by DOI 10.1158/1078-0432.CCR-21-3471.
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Abstract
While metastatic osteosarcoma is rare in humans, it is the most common bone tumor found in any breed of dog. Given the genetic similarities between canine and human osteosarcomas, canine clinical trials allow for rapid testing and drug repurposing at a speed that cannot be achieved using patients with osteosarcoma. See related article by Regan et al., p. 662.
Medical subject headings
- Bone Neoplasms
- Dog Diseases
- Osteosarcoma