Replication of SARS-CoV-2 in adipose tissue determines organ and systemic lipid metabolism in hamsters and humans.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 34895500.
- Also identified by DOI 10.1016/j.cmet.2021.12.002 and PMC identifier 8663969.
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Abstract
Zickler et al. describe SARS-CoV-2 RNA in post-mortem samples of human adipose tissue. In the hamster model, SARS-CoV-2 propagation in adipose tissue leads to specific changes in lipid metabolism, which are reflected in lipidome patterns of hamster and human plasma.
Medical subject headings
- Adipose Tissue
- COVID-19
- Lipid Metabolism
- Liver
- Lung
- SARS-CoV-2
- Virus Replication