An ionizable lipid toolbox for RNA delivery.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 34903741.
- Also identified by DOI 10.1038/s41467-021-27493-0 and PMC identifier 8668901.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Recent years have witnessed incredible growth in RNA therapeutics, which has benefited significantly from decades of research on lipid nanoparticles, specifically its key component—the ionizable lipid. This comment discusses the major ionizable lipid types, and provides perspectives for future development.
Medical subject headings
- Drug Delivery Systems
- Lipids
- RNA