Tranexamic acid use in pelvic and/or acetabular fracture surgery: A systematic review and meta-analysis.
systematic_review · Level I
Where this comes from
- Record sourced from PubMed, PMID 34924726.
- Also identified by DOI 10.1016/j.jor.2021.11.018 and PMC identifier 8648565.
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Abstract
The purpose of this study is to determine whether tranexamic acid (TXA) use was associated with lower rates of blood transfusion in patients undergoing pelvic and/or acetabular fracture surgery. Four studies were included, 3 of which were included in the pooled data analysis for a total of 308 patients. The transfusion rate was significantly lower in the TXA group (44%) compared with the non-TXA group (57%) (P = 0.02). TXA use was associated with a significantly lower transfusion rate in patients who underwent pelvic and/or acetabular fracture surgery. Level 3. Systematic review of retrospective cohort studies and prospective randomized controlled trials.
Anatomy
- pelvis
- hip