In hypertension, a quadpill containing quarter doses of 4 BP drugs reduced BP at 12 wk vs. standard-dose monotherapy.

Brown, Krysta; Donato Md, Anthony A · Ann Intern Med · 2022

rct · Level II

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Abstract

Chow CK, Atkins ER, Hillis GS, et al. <b>Initial treatment with a single pill containing quadruple combination of quarter doses of blood pressure medicines versus standard dose monotherapy in patients with hypertension (QUARTET): a phase 3, randomised, double-blind, active-controlled trial.</b> Lancet. 2021;398:1043-52. 34469767.

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