Coronavirus Disease 2019 Messenger RNA Vaccines Associated With Delayed Onset of Breakthrough Infections and Fewer Radiographic Abnormalities.

Li, Xin; Chan, Jacky Man Chun; Lam, Bosco; Lung, David Christopher; Lung, Kwok Cheung; Chow, Christina Kin Yi; Tam, Tracey; Chiu, Kelvin Hei Yeung et al. · Clin Infect Dis · 2022

retrospective_cohort · Level III

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Abstract

This retrospective study of incoming travelers with coronavirus disease 2019 showed that individuals immunized by messenger RNA vaccines had significantly longer postvaccination intervals (median, 30.5 days) to breakthrough infection, lower white blood cell counts and lactate dehydrogenase levels on admission, and fewer radiographic abnormalities than those immunized by inactivated virus vaccine, who paradoxically had lower respiratory viral load.

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