Enteric glia bring fresh WNT to the intestinal stem cell niche.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 34995494.
- Also identified by DOI 10.1016/j.stem.2021.12.003.
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Abstract
Intestinal stem cells continuously self-renew and differentiate into a variety of specialized epithelial cells that maintain gut health. New research in this issue of Cell Stem Cell (Baghdadi et al., 2022) shows that enteric glial cells regulate the intestinal stem cell niche during regeneration and disease through the production of WNT ligands.
Medical subject headings
- Neuroglia
- Stem Cell Niche