High False-Positive Rate of (1,3)-β-D-Glucan in Onco-Hematological Patients Receiving Immunoglobulins and Therapeutic Antibodies.

Tschopp, Jonathan; Brunel, Anne Sophie; Spertini, Olivier; Croxatto, Anthony; Lamoth, Frederic; Bochud, Pierre Yves · Clin Infect Dis · 2022

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Abstract

Immunoglobulins and/or therapeutic antibody preparations are associated with a high rate of false-positive (1,3)-β-D-glucan (BDG) tests in onco-hematological patients routinely screened for fungal infections. The benefit of BDG monitoring shall be balanced against the risk of false-positive tests leading to unnecessary investigations and costs in this population.

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