Thermometer: a webserver to predict protein thermal stability.

Miotto, Mattia; Armaos, Alexandros; Di Rienzo, Lorenzo; Ruocco, Giancarlo; Milanetti, Edoardo; Tartaglia, Gian Gaetano · Bioinformatics · 2022

basic_science · Level V

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Abstract

Thermal properties of proteins are of great importance for a number of theoretical and practical implications. Predicting the thermal stability of a protein is a difficult and still scarcely addressed task. Here, we introduce Thermometer, a webserver to assess the thermal stability of a protein using structural information. Thermometer is implemented as a publicly available, user-friendly interface. Our server can be found at the following link (all major browser supported): http://service.tartaglialab.com/new_submission/thermometer_file. Supplementary data are available at Bioinformatics online.

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