The importance of offering early genetic testing in everyone with amyotrophic lateral sclerosis.

Salmon, Kristiana; Kiernan, Matthew C; Kim, Seung H; Andersen, Peter M; Chio, Adriano; van den Berg, Leonard H; Van Damme, Philip; Al-Chalabi, Ammar et al. · Brain · 2022

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Abstract

Several genetically-targeted therapies are being developed for ALS. Research is increasingly supportive of a greater incidence of clinically actionable variants in sporadic ALS than previously reported. Salmon <i>et al</i>. outline the need to improve access, and offer genetic testing to all people diagnosed with ALS.

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