MeRIPseqPipe: an integrated analysis pipeline for MeRIP-seq data based on Nextflow.

Bao, Xiaoqiong; Zhu, Kaiyu; Liu, Xuefei; Chen, Zhihang; Luo, Ziwei; Zhao, Qi; Ren, Jian; Zuo, Zhixiang · Bioinformatics · 2022

other · Level V

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Abstract

MeRIPseqPipe is an integrated and automatic pipeline that can provide users a friendly solution to perform in-depth mining of MeRIP-seq data. It integrates many functional analysis modules, range from basic processing to downstream analysis. All the processes are embedded in Nextflow with Docker support, which ensures high reproducibility and scalability of the analysis. MeRIPseqPipe is particularly suitable for analyzing a large number of samples at once with a simple command. The final output directory is structured based on each step and tool. And visualization reports containing various tables and plots are provided as HTML files. MeRIPseqPipe is freely available at https://github.com/canceromics/MeRIPseqPipe. Supplementary data are available at Bioinformatics online.

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