Unusual Diffuse Ground-Glass Opacities in the Lungs on 18F-FDG PET/CT: A Case of Melanoma With Pulmonary Metastasis.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 35025785.
- Also identified by DOI 10.1097/RLU.0000000000004031.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
A 61-year-old man was diagnosed with a malignant melanoma and underwent a resection; he presented with progressive dyspnea after treatment with interferon for 2 months. 18F-FDG PET/CT scan revealed diffuse ground-glass opacities (GGOs) in both lungs with mildly elevated 18F-FDG uptake, similar to that observed with interstitial inflammation. However, a lung biopsy confirmed that the diffuse GGOs were pulmonary metastases of melanoma and were positive for the BRAF mutation. The diffuse GGOs and the progressive dyspnea disappeared after BRAF-targeted therapy. This represents an unusual case of lung metastases from melanoma, mistakenly interpreted as lung inflammation induced by immunotherapy.
Medical subject headings
- Lung Neoplasms
- Melanoma