Case of Adult Metastatic Medulloblastoma Demonstrated on 18F-DOPA PET/CT.

Marafi, Fahad; Sadeq, Alyaa; Esmail, Abdulredha; Usmani, Sharjeel · Clin Nucl Med · 2022

case_report · Level V

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Abstract

18F-DOPA is a promising radiotracer used for both staging and restaging of primary brain tumors based on increased transport via the L-type large neutral amino acid transport system in tumor cells. Adult medulloblastoma is extremely rare. We present a case of 25-year-old man with posterior fossa medulloblastoma treated with surgery followed by chemotherapy and radiotherapy 5 years back, which later developed metastasis to left cerebral lobe treated with gamma knife followed by surgical debulking. Recent 18F-DOPA PET/CT demonstrates recurrence and disease progression on follow-up scan. 18F-DOPA PET/CT is extremely useful for characterizing brain tumors, response assessment, and prognosis.

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