Increased Accumulation of 18F-FDG Incidentally Observed in Hyperacute Cerebral Infarction.

Sotome, Wataru; Ito, Yoshiaki; Higuchi, Nobuya; Asami, Yuta; Satomi, Nao · Clin Nucl Med · 2022

case_report · Level V

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Abstract

A 75-year-old man with lung cancer undertook an 18F-FDG PET/CT for staging. He presented neurological symptoms immediately after the 30-minute scan. An emergent MRI study revealed hyperacute cerebral infarction with occlusion of a left MCA branch. At PET/CT, an increased 18F-FDG uptake was observed in the corresponding areas of infarction. In literature, acceleration of compensatory anaerobic glycolysis has been proposed as 1 of the causes of increased uptake in the penumbra of acute cerebral infarction, and a similar process was hypothesized in this case. In addition, a decreased 18F-FDG uptake in the ipsilateral thalamus was noted on the PET/CT images.

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