Trend in Sensitivity of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Serology One Year After Mild and Asymptomatic Coronavirus Disease 2019 (COVID-19): Unpacking Potential Bias in Seroprevalence Studies.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 35026841.
- Also identified by DOI 10.1093/cid/ciac020 and PMC identifier 8807225.
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Abstract
A key aim of serosurveillance during the coronavirus disease 2019 (COVID-19) pandemic has been to estimate the prevalence of prior infection, by correcting crude seroprevalence against estimated test performance for polymerase chain reaction (PCR)-confirmed COVID-19. We show that poor generalizability of sensitivity estimates to some target populations may lead to substantial underestimation of case numbers.
Medical subject headings
- COVID-19
- SARS-CoV-2