Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Transmission Dynamics and Immune Responses in a Household of Vaccinated Persons.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 35037050.
- Also identified by DOI 10.1093/cid/ciac029 and PMC identifier 8807302.
- Licence recorded as CC BY-NC-ND.
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Abstract
While SARS-CoV-2 vaccines prevent severe disease effectively, postvaccination "breakthrough" COVID-19 infections and transmission among vaccinated individuals remain ongoing concerns. We present an in-depth characterization of transmission and immunity among vaccinated individuals in a household, revealing complex dynamics and unappreciated comorbidities, including autoimmunity to type 1 interferon in the presumptive index case.
Medical subject headings
- COVID-19
- SARS-CoV-2