Pituitary Metastasis of Renal Cell Carcinoma Characterized by 18F-Prostate-Specific Membrane Antigen-1007 PET/CT.

Tariq, Arsalan; Raman, Vignesh; Alexander, Hamish; Roberts, Matthew J; Thomas, Paul · Clin Nucl Med · 2022

case_report · Level V

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Abstract

Renal cell carcinoma (RCC) is one of the most common oncological diagnoses worldwide. Accurate staging and restaging imaging continue to be a priority in clinical practice as 20% to 30% of patients present with advanced metastatic disease at diagnosis, and 20% to 30% develop recurrence after surgical resection. We present a case of a 71-year-old man presenting with an isolated pituitary RCC metastasis accurately defined on 18F-prostate-specific membrane antigen-1007 masquerading as a macroadenoma on conventional imaging (CT and MRI). This demonstrates the potential utility of 18F-prostate-specific membrane antigen-1007 in characterizing RCC brain metastasis.

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