Impaired Intrauterine Growth in the Context of Maternal Hookworm Infection During Gestation.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 35091745.
- Also identified by DOI 10.1093/infdis/jiac025 and PMC identifier 9113511.
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Abstract
Hookworm infection is associated with poor nutritional outcomes, anemia, and impaired cognitive performance. We examined the association between maternal hookworm infection and birth outcomes in a cohort of women in Leyte, Philippines. We observed poor intrauterine growth characteristics associated with maternal hookworm only among male offspring, with lower birth weight, head circumference, and placental surface area. Male neonates also had higher insulin-like growth factor 2 (IGF-2) and lower adiponectin in cord blood. These data intriguingly suggest nutritional impacts of maternal hookworm infection during pregnancy may be divergent based on sex of the offspring.
Medical subject headings
- Hookworm Infections
- Placenta