In COVID-19, escalated- vs. prophylactic-dose anticoagulation does not reduce mortality and increases major bleeding.

Chaudhuri, Dipayan; Rochwerg, Bram · Ann Intern Med · 2022

meta_analysis · Level I

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Abstract

Ortega-Paz L, Galli M, Capodanno D, et al. <b>Safety and efficacy of different prophylactic anticoagulation dosing regimens in critically and non-critically ill patients with COVID-19: a systematic review and meta-analysis of randomized controlled trials.</b> Eur Heart J Cardiovasc Pharmacother. 2021. [Epub ahead of print.] 34519777.

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