Forgetting in obesity: The pregnenolone link.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 35108507.
- Also identified by DOI 10.1016/j.cmet.2022.01.006.
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Abstract
Cognitive dysfunction is often diagnosed in people with obesity and associated metabolic disorders. In the latest issue of Cell Metabolism, Ramírez et al. highlight an impaired production of the neurosteroid pregnenolone in the hypothalamus as a mechanism for obesity-induced cognitive impairment in both rodent models and patients with obesity.
Medical subject headings
- Hypothalamus
- Pregnenolone