Effectiveness of BNT162b2 and mRNA-1273 Second Doses and Boosters for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and SARS-CoV-2-Related Hospitalizations: A Statewide Report From the Minnesota Electronic Health Record Consortium.

Drawz, Paul E; DeSilva, Malini; Bodurtha, Peter; Vazquez Benitez, Gabriela; Murray, Anne; Chamberlain, Alanna M; Dudley, R Adams; Waring, Stephen et al. · Clin Infect Dis · 2022

retrospective_cohort · Level III

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Abstract

Using vaccine data combined with electronic health records, we report that mRNA boosters provide greater protection than a 2-dose regimen against SARS-CoV-2 infection and related hospitalizations. The benefit of a booster was more evident in the elderly and those with comorbidities.

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