Microbiome Modelling Toolbox 2.0: efficient, tractable modelling of microbiome communities.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 35157025.
- Also identified by DOI 10.1093/bioinformatics/btac082 and PMC identifier 9004645.
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Abstract
Constraint-Based Reconstruction and Analysis (COBRA) is a widely used approach for the interrogation and stratification of microbiome samples, yet applications to large-scale cohorts are hampered by limited scalability and efficiency of simulations. We substantially improved the computation speed and scalability of a previous implementation for the construction and interrogation of personalized constraint-based microbiome models as well as implemented additional functionalities for analysis and visualization. Microbiome Modelling Toolbox and tutorials are freely available as part of the COBRA Toolbox at https://git.io/microbiomeModelingToolbox.
Medical subject headings
- Software
- Microbiota