Time matters: Human blastoids resemble the sequence of blastocyst development.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 35180387.
- Also identified by DOI 10.1016/j.cell.2022.01.005.
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Abstract
In a recent issue of Nature, Kagawa et al. reported a highly efficient and robust protocol for generating human blastoids from naive human pluripotent stem cells. The blastoids resemble human blastocysts, follow the sequential lineage specification of blastocyst development, and can attach to endometrial cells with the polar trophectoderm to model implantation.
Medical subject headings
- Embryonic Development
- Pluripotent Stem Cells