How collagen becomes 'stiff'.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 35188461.
- Also identified by DOI 10.7554/eLife.77041 and PMC identifier 8860450.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Oxidative stress following a lung injury can alter the structure of collagen, causing it to stiffen and trigger the formation of a fibrotic scar that further hardens the tissue.
Medical subject headings
- Cicatrix
- Collagen